7YDG

Crystal structure of human SARS2 catalytic domain with a disease related mutation

Summary for 7YDG

• Entry DOI: 10.2210/pdb7ydg/pdb
• Related: 7YDF
• Descriptor: Serine--tRNA ligase, mitochondrial (1 entity in total)
• Functional Keywords: mitochondrial seryl-trna synthetase, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 157639.31

Authors

Wu, S.,Li, P.,Zhou, X.L.,Fang, P. (deposition date: 2022-07-04, release date: 2022-11-02, Last modification date: 2023-11-29)

• Primary citation: Yu, T.,Zhang, Y.,Zheng, W.Q.,Wu, S.,Li, G.,Zhang, Y.,Li, N.,Yao, R.,Fang, P.,Wang, J.,Zhou, X.L.; Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease.; Nucleic Acids Res., 50:11755-11774, 2022; PubMed: 36350636; DOI: 10.1093/nar/gkac1028

Experimental method

X-RAY DIFFRACTION (3.2 Å)