7YCK

Crystal structure of SARS-CoV-2 Spike RBD in complex with FP-12A Fab

7YCK の概要

• エントリーDOI: 10.2210/pdb7yck/pdb
• 分子名称: Spike protein S1, FP-12A Fab heavy chain, FP-12A Fab light chain, ... (6 entities in total)
• 機能のキーワード: antibody, sars-cov-2, spike, rbd, class 4, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 141498.96

構造登録者

Nguyen, V.H.T.,Chen, X. (登録日: 2022-07-01, 公開日: 2023-02-01, 最終更新日: 2023-11-29)

• 主引用文献: Huang, K.A.,Chen, X.,Mohapatra, A.,Nguyen, H.T.V.,Schimanski, L.,Tan, T.K.,Rijal, P.,Vester, S.K.,Hills, R.A.,Howarth, M.,Keeffe, J.R.,Cohen, A.A.,Kakutani, L.M.,Wu, Y.M.,Shahed-Al-Mahmud, M.,Chou, Y.C.,Bjorkman, P.J.,Townsend, A.R.,Ma, C.; Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.; Nat Commun, 14:311-311, 2023; PubMed: 36658148; DOI: 10.1038/s41467-023-35949-8

実験手法

X-RAY DIFFRACTION (2.6 Å)