7Y99

Crystal Structure Analysis of cp2 bound BCLxl

Summary for 7Y99

• Entry DOI: 10.2210/pdb7y99/pdb
• Descriptor: Bcl-2-like protein 1, CP2 peptide, N-(2-acetamidoethyl)-4-(4,5-dihydro-1,3-thiazol-2-yl)benzamide, ... (4 entities in total)
• Functional Keywords: complex, apoptosis
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 17911.04

Authors

Li, F.W.,Liu, C.,Wu, C.L.,Wu, D.L. (deposition date: 2022-06-24, release date: 2023-09-27, Last modification date: 2024-02-28)

• Primary citation: Li, F.,Liu, J.,Liu, C.,Liu, Z.,Peng, X.,Huang, Y.,Chen, X.,Sun, X.,Wang, S.,Chen, W.,Xiong, D.,Diao, X.,Wang, S.,Zhuang, J.,Wu, C.,Wu, D.; Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.; Nat Commun, 15:1476-1476, 2024; PubMed: 38368459; DOI: 10.1038/s41467-024-45848-1

Experimental method

X-RAY DIFFRACTION (1.9 Å)