7Y65

Cryo-EM structure of C5a peptide-bound C5aR1 in complex with Gi protein

7Y65 の概要

• エントリーDOI: 10.2210/pdb7y65/pdb
• EMDBエントリー: 33634
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: complex, agonist, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 155470.34

構造登録者

Feng, Y.Y.,Zhao, C.,Yan, W.,Shao, Z.H. (登録日: 2022-06-18, 公開日: 2023-03-01, 最終更新日: 2023-04-19)

• 主引用文献: Feng, Y.,Zhao, C.,Deng, Y.,Wang, H.,Ma, L.,Liu, S.,Tian, X.,Wang, B.,Bin, Y.,Chen, P.,Yan, W.,Fu, P.,Shao, Z.; Mechanism of activation and biased signaling in complement receptor C5aR1.; Cell Res., 33:312-324, 2023; PubMed: 36806352; DOI: 10.1038/s41422-023-00779-2

実験手法

ELECTRON MICROSCOPY (3.2 Å)