7Y58

CryoEM structure of QacA (D411N), an antibacterial efflux transporter from Staphylococcus aureus

7Y58 の概要

• エントリーDOI: 10.2210/pdb7y58/pdb
• EMDBエントリー: 33612
• 分子名称: Antiseptic resistance protein, Single-domain Indian camelid antibody (A4), single-domain indian camelid antibody(B7) (3 entities in total)
• 機能のキーワード: drug proton antiporter, major facilitator superfamily(mfs), staphylococcus aureus, antibacterial efflux, qaca, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• 由来する生物種: Staphylococcus aureus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 82208.52

構造登録者

Penmatsa, A.,Majumder, P. (登録日: 2022-06-16, 公開日: 2023-07-12, 最終更新日: 2023-11-22)

• 主引用文献: Majumder, P.,Ahmed, S.,Ahuja, P.,Athreya, A.,Ranjan, R.,Penmatsa, A.; Cryo-EM structure of antibacterial efflux transporter QacA from Staphylococcus aureus reveals a novel extracellular loop with allosteric role.; Embo J., 42:e113418-e113418, 2023; PubMed: 37458117; DOI: 10.15252/embj.2023113418

実験手法

ELECTRON MICROSCOPY (3.8 Å)