7Y4M
Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanyl-N6-((benzyloxy)carbonyl)-L-lysine
Summary for 7Y4M
Entry DOI | 10.2210/pdb7y4m/pdb |
Related | 7Y4K |
Descriptor | Ricin A chain, (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase inhibitor, hydrolase |
Biological source | Ricinus communis (castor bean) |
Total number of polymer chains | 1 |
Total formula weight | 31762.62 |
Authors | Katakura, S.,Goto, M.,Ohba, T.,Kawata, R.,Nagatsu, K.,Higashi, S.,Matsumoto, K.,Kurisu, K.,Ohtsuka, K.,Saito, R. (deposition date: 2022-06-15, release date: 2022-11-16, Last modification date: 2023-11-29) |
Primary citation | Saito, R.,Goto, M.,Katakura, S.,Ohba, T.,Kawata, R.,Nagatsu, K.,Higashi, S.,Kurisu, K.,Matsumoto, K.,Ohtsuka, K. Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain. Plos One, 17:e0277770-e0277770, 2022 Cited by PubMed: 36508422DOI: 10.1371/journal.pone.0277770 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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