7Y2P
Crystal structure of CUG repeat RNA duplex containing A-U base pair and U-U mismatches
Summary for 7Y2P
Entry DOI | 10.2210/pdb7y2p/pdb |
Descriptor | RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3'), RNA (5'-R(P*UP*UP*CP*UP*GP*CP*AP*GP*CP*UP*GP*AP*A)-3') (3 entities in total) |
Functional Keywords | cug repeats, myotonic dystrophy type 1 (dm1), u-u mismatches, rna, a-u base pair |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 8213.93 |
Authors | Wang, S.C.,Satange, R.B.,Hou, M.H. (deposition date: 2022-06-09, release date: 2023-05-31, Last modification date: 2023-11-29) |
Primary citation | Wang, S.C.,Chen, Y.T.,Satange, R.,Chu, J.W.,Hou, M.H. Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1. J.Biol.Chem., 299:104864-104864, 2023 Cited by PubMed: 37245780DOI: 10.1016/j.jbc.2023.104864 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.58 Å) |
Structure validation
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