7Y24

Cryo-EM structure of the octreotide-bound SSTR2-miniGo-scFv16 complex

Summary for 7Y24

• Entry DOI: 10.2210/pdb7y24/pdb
• Related: 7D77
• EMDB information: 33585
• Descriptor: Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, somatostatin receptor, g protein, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 132414.42

Authors

Chen, S.,Zheng, S. (deposition date: 2022-06-09, release date: 2022-10-19, Last modification date: 2023-02-15)

• Primary citation: Chen, S.,Teng, X.,Zheng, S.; Molecular basis for the selective G protein signaling of somatostatin receptors.; Nat.Chem.Biol., 19:133-140, 2023; PubMed: 36138141; DOI: 10.1038/s41589-022-01130-3

Experimental method

ELECTRON MICROSCOPY (3.25 Å)