7Y09

Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP

Summary for 7Y09

• Entry DOI: 10.2210/pdb7y09/pdb
• EMDB information: 33538
• Descriptor: Putative erythrocyte membrane protein, Immunoglobulin heavy constant mu, Immunoglobulin J chain, ... (5 entities in total)
• Functional Keywords: malaria, immunoglobin, immune system
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 12
• Total formula weight: 511984.88

Authors

Shen, H.,Ji, C.,Xiao, J. (deposition date: 2022-06-03, release date: 2023-03-29, Last modification date: 2024-05-08)

• Primary citation: Ji, C.,Shen, H.,Su, C.,Li, Y.,Chen, S.,Sharp, T.H.,Xiao, J.; Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.; Nat Commun, 14:2650-2650, 2023; PubMed: 37156765; DOI: 10.1038/s41467-023-38320-z

Experimental method

ELECTRON MICROSCOPY (3.71 Å)