7XY6
Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
Summary for 7XY6
Entry DOI | 10.2210/pdb7xy6/pdb |
EMDB information | 33512 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
Functional Keywords | g protein coupled-receptor, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 145739.78 |
Authors | Zhang, J.Y.,Chen, Y.,Hua, T.,Song, G.J. (deposition date: 2022-05-31, release date: 2023-05-03, Last modification date: 2023-05-31) |
Primary citation | Chen, Y.,Zhang, J.,Weng, Y.,Xu, Y.,Lu, W.,Liu, W.,Liu, M.,Hua, T.,Song, G. Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex. Sci Adv, 8:eadd3709-eadd3709, 2022 Cited by PubMed: 36563137DOI: 10.1126/sciadv.add3709 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.99 Å) |
Structure validation
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