7XXT

HapR Quadruple mutant, bound to IMTVC-212

7XXT の概要

• エントリーDOI: 10.2210/pdb7xxt/pdb
• 分子名称: Hemagglutinin/protease regulatory protein, DIMETHYL SULFOXIDE, 1-((5-phenylthiophen-2-yl)sulfonyl)-1H-pyrazole, ... (4 entities in total)
• 機能のキーワード: hapr master regulator, transcription
• 由来する生物種: Vibrio cholerae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24016.83

構造登録者

Basu Choudhury, G.,Chaudhari, V.,Ray Chaudhuri, S.,Datta, S. (登録日: 2022-05-30, 公開日: 2023-02-22, 最終更新日: 2023-11-29)

• 主引用文献: Sen, H.,Choudhury, G.B.,Pawar, G.,Sharma, Y.,Bhalerao, S.E.,Chaudhari, V.D.,Datta, S.,Raychaudhuri, S.; Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective.; Int.J.Biol.Macromol., 233:123495-123495, 2023; PubMed: 36739058; DOI: 10.1016/j.ijbiomac.2023.123495

実験手法

X-RAY DIFFRACTION (2.501 Å)