7XX3

Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)

7XX3 の概要

• エントリーDOI: 10.2210/pdb7xx3/pdb
• 分子名称: Superoxide dismutase [Cu-Zn], ZINC ION, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: superoxide dismutase, protein aggregation, modulator, toxic trimer, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 192834.62

構造登録者

Padmanabhan, B.,Unni, S. (登録日: 2022-05-28, 公開日: 2023-12-13)

• 主引用文献: Unni, S.,Padmanabhan, B.; Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS); To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)