7XWQ

Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R)-2-(2-chloro-4-hydroxyphenyl)-3-(4-hydroxyphenyl)propanenitrile

7XWQ の概要

• エントリーDOI: 10.2210/pdb7xwq/pdb
• 分子名称: Estrogen receptor beta, SRC peptide, (2~{R})-2-(2-chloranyl-4-oxidanyl-phenyl)-3-(4-hydroxyphenyl)propanenitrile, ... (4 entities in total)
• 機能のキーワード: inhibitor, transcription, transcription-inhibitor complex, transcription/inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 58725.77

構造登録者

Furuya, N.,Handa, C. (登録日: 2022-05-27, 公開日: 2022-07-20, 最終更新日: 2023-11-29)

• 主引用文献: Handa, C.,Yamazaki, Y.,Yonekubo, S.,Furuya, N.,Momose, T.,Ozawa, T.,Furuishi, T.,Fukuzawa, K.,Yonemochi, E.; Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives.; J.Steroid Biochem.Mol.Biol., 222:106152-106152, 2022; PubMed: 35810932; DOI: 10.1016/j.jsbmb.2022.106152

実験手法

X-RAY DIFFRACTION (1.89 Å)