7XWM

structure of patulin-detoxifying enzyme Y155F/V187K with NADPH

Summary for 7XWM

Entry DOI	10.2210/pdb7xwm/pdb
Descriptor	Short-chain dehydrogenase/reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	dehydrogenases/reductase, oxidoreductase
Biological source	Meyerozyma guilliermondii
Total number of polymer chains	4
Total formula weight	115321.00
Authors	Dai, L.,Li, H.,Hu, Y.,Guo, R.T.,Chen, C.C. (deposition date: 2022-05-26, release date: 2023-04-12, Last modification date: 2023-11-29)
Primary citation	Dai, L.,Li, H.,Huang, J.W.,Hu, Y.,He, M.,Yang, Y.,Min, J.,Guo, R.T.,Chen, C.C. Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222:421-428, 2022 Cited by PubMed: 36176222 DOI: 10.1016/j.ijbiomac.2022.09.121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation