7XW2
Cryo-EM structure of human DICER-pre-miRNA in a dicing state
Summary for 7XW2
Entry DOI | 10.2210/pdb7xw2/pdb |
EMDB information | 33489 |
Descriptor | Endoribonuclease Dicer, RNA (73-MER), CALCIUM ION (3 entities in total) |
Functional Keywords | dicer, rnaseiii, rna-binding, micro-rna processing, gene regulation, gene regulation-rna complex, gene regulation/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 242371.27 |
Authors | Lee, H.,Roh, S.-H. (deposition date: 2022-05-26, release date: 2023-03-08, Last modification date: 2024-07-03) |
Primary citation | Lee, Y.Y.,Lee, H.,Kim, H.,Kim, V.N.,Roh, S.H. Structure of the human DICER-pre-miRNA complex in a dicing state. Nature, 615:331-338, 2023 Cited by PubMed: 36813958DOI: 10.1038/s41586-023-05723-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.04 Å) |
Structure validation
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