7XV3

Cryo-EM structure of LPS-bound GPR174 in complex with Gs protein

Summary for 7XV3

• Entry DOI: 10.2210/pdb7xv3/pdb
• EMDB information: 33479
• Descriptor: Probable G-protein coupled receptor 174, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Engineered G protein subunit S (mini-Gs), ... (7 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 144074.61

Authors

He, Y.,Liang, J. (deposition date: 2022-05-20, release date: 2023-02-15, Last modification date: 2023-03-08)

• Primary citation: Liang, J.,Inoue, A.,Ikuta, T.,Xia, R.,Wang, N.,Kawakami, K.,Xu, Z.,Qian, Y.,Zhu, X.,Zhang, A.,Guo, C.,Huang, Z.,He, Y.; Structural basis of lysophosphatidylserine receptor GPR174 ligand recognition and activation.; Nat Commun, 14:1012-1012, 2023; PubMed: 36823105; DOI: 10.1038/s41467-023-36575-0

Experimental method

ELECTRON MICROSCOPY (2.76 Å)