7XRP

Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement)

7XRP の概要

• エントリーDOI: 10.2210/pdb7xrp/pdb
• EMDBエントリー: 33416
• 分子名称: Spike protein S1, C5G2 nanobody, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, neutralizing nanobody, cryo-em, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 68123.13

構造登録者

Liu, L.,Sun, H.,Jiang, Y.,Liu, X.,Zhao, D.,Zheng, Q.,Li, S.,Xia, N. (登録日: 2022-05-11, 公開日: 2022-10-05)

• 主引用文献: Zhao, D.,Liu, L.,Liu, X.,Zhang, J.,Yin, Y.,Luan, L.,Jiang, D.,Yang, X.,Li, L.,Xiong, H.,Xing, D.,Zheng, Q.,Xia, N.,Tao, Y.,Li, S.,Huang, H.; A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode.; J Nanobiotechnology, 20:411-411, 2022; PubMed: 36109732; DOI: 10.1186/s12951-022-01619-y

実験手法

ELECTRON MICROSCOPY (3.88 Å)