7XOE

Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Prefusion state)

7XOE の概要

• エントリーDOI: 10.2210/pdb7xoe/pdb
• EMDBエントリー: 33346
• 分子名称: Spike glycoprotein,peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: spike, mrna vaccine, sars-cov-2, s clycoprotein, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 438197.62

構造登録者

Wu, Z.,Yu, Z.,Tan, S.,Lu, J.,Lu, G.,Lin, J. (登録日: 2022-05-01, 公開日: 2024-02-14)

• 主引用文献: Tan, S.,Zhao, J.,Hu, X.,Li, Y.,Wu, Z.,Lu, G.,Yu, Z.,Du, B.,Liu, Y.,Li, L.,Chen, Y.,Li, Y.,Yao, Y.,Zhang, X.,Rao, J.,Gao, G.,Peng, Y.,Liu, H.,Yuan, Z.,Liu, J.,Wang, Q.,Hu, H.,Gao, X.,Zhou, H.,Yu, H.,Xu, Y.,Yu, W.,Feng, L.,Wang, M.,Shan, C.,Lu, J.,Lin, J.; Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.; Sci Bull (Beijing), 68:3192-3206, 2023; PubMed: 37993332; DOI: 10.1016/j.scib.2023.11.024

実験手法

ELECTRON MICROSCOPY (3.9 Å)