7XLY

Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis

7XLY の概要

• エントリーDOI: 10.2210/pdb7xly/pdb
• 分子名称: Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION (2 entities in total)
• 機能のキーワード: acetyl-coa acetyltransferase, fatty acid metabolism, mycobacterium tuberculosis, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 184796.55

構造登録者

Singh, R.,Kundu, P.,Singh, B.K.,Bhattacharyya, S.,Das, A.K. (登録日: 2022-04-23, 公開日: 2023-04-26, 最終更新日: 2023-08-30)

• 主引用文献: Singh, R.,Kundu, P.,Mishra, V.K.,Singh, B.K.,Bhattacharyya, S.,Das, A.K.; Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties.; Febs J., 290:3997-4022, 2023; PubMed: 37026388; DOI: 10.1111/febs.16792

実験手法

X-RAY DIFFRACTION (2.9 Å)