7XLV

Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (G7I mutant)

7XLV の概要

• エントリーDOI: 10.2210/pdb7xlv/pdb
• 分子名称: DNA (5'-D(*CP*AP*CP*CP*TP*AP*IP*CP*GP*A)-3'), (4S)-2-METHYL-2,4-PENTANEDIOL, SILVER ION, ... (4 entities in total)
• 機能のキーワード: silver, nanocluster, dna
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8165.63

構造登録者

Kondo, J.,Cerretani, C.,Vosch, T. (登録日: 2022-04-23, 公開日: 2022-07-13, 最終更新日: 2023-11-29)

主引用文献

Cerretani, C.,Liisberg, M.B.,Ruck, V.,Kondo, J.,Vosch, T.
The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster.
Nanoscale Adv, 4:3212-3217, 2022

PubMed Abstract: The effect of replacing guanosines with inosines in the two stabilizing strands (5'-CACCTAGCGA-3') of the NIR emissive DNA-AgNC was investigated. The spectroscopic behavior of the inosine mutants is position-dependent: when the guanosine in position 7 was exchanged, the nanosecond fluorescence decay time shortened, while having the inosine in position 9 made the decay time longer. Thanks to structural information gained from single crystal X-ray diffraction measurements, it was possible to propose a mechanistic origin for the observed changes.

PubMed: 36132821
DOI: 10.1039/d2na00325b

実験手法

X-RAY DIFFRACTION (1.1 Å)