7XKF

Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex at lower state

7XKF の概要

• エントリーDOI: 10.2210/pdb7xkf/pdb
• EMDBエントリー: 33250
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: adgrg2, complex, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 140384.10

構造登録者

Guo, S.C.,Xiao, P.,Lin, H.,Sun, J.P.,Yu, X. (登録日: 2022-04-19, 公開日: 2022-08-10, 最終更新日: 2023-03-15)

• 主引用文献: Lin, H.,Xiao, P.,Bu, R.Q.,Guo, S.,Yang, Z.,Yuan, D.,Zhu, Z.L.,Zhang, C.X.,He, Q.T.,Zhang, C.,Ping, Y.Q.,Zhao, R.J.,Ma, C.S.,Liu, C.H.,Zhang, X.N.,Jiang, D.,Huang, S.,Xi, Y.T.,Zhang, D.L.,Xue, C.Y.,Yang, B.S.,Li, J.Y.,Lin, H.C.,Zeng, X.H.,Zhao, H.,Xu, W.M.,Yi, F.,Liu, Z.,Sun, J.P.,Yu, X.; Structures of the ADGRG2-G s complex in apo and ligand-bound forms.; Nat.Chem.Biol., 18:1196-1203, 2022; PubMed: 35982227; DOI: 10.1038/s41589-022-01084-6

実験手法

ELECTRON MICROSCOPY (2.4 Å)