7XK8

Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25

7XK8 の概要

• エントリーDOI: 10.2210/pdb7xk8/pdb
• EMDBエントリー: 33247
• 分子名称: Neuromedin-U-25, Neuromedin-U receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total)
• 機能のキーワード: gpcr, complex, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 134838.01

構造登録者

Zhao, W.,Wenru, Z.,Mu, W.,Minmin, L.,Shutian, C.,Tingting, T.,Gisela, S.,Holger, W.,Albert, B.,Cuiying, Y.,Xiaojing, C.,Han, S.,Wu, B.,Zhao, Q. (登録日: 2022-04-19, 公開日: 2023-02-22)

• 主引用文献: Zhao, W.,Zhang, W.,Wang, M.,Lu, M.,Chen, S.,Tang, T.,Schnapp, G.,Wagner, H.,Brennauer, A.,Yi, C.,Chu, X.,Han, S.,Wu, B.,Zhao, Q.; Ligand recognition and activation of neuromedin U receptor 2.; Nat Commun, 13:7955-7955, 2022; PubMed: 36575163; DOI: 10.1038/s41467-022-34814-4

実験手法

ELECTRON MICROSCOPY (3.3 Å)