7XIU
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
Summary for 7XIU
Entry DOI | 10.2210/pdb7xiu/pdb |
Descriptor | Reverse Transcriptase RNase H domain, MANGANESE (II) ION, [4-(hydroxymethyl)phenyl] 5-nitrothiophene-2-carboxylate, ... (5 entities in total) |
Functional Keywords | ribonuclease, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 1 |
Total formula weight | 17352.25 |
Authors | Lu, H.,Komukai, Y.,Usami, K.,Guo, Y.,Qiao, X.,Nukaga, M.,Hoshino, T. (deposition date: 2022-04-14, release date: 2022-04-27, Last modification date: 2023-11-29) |
Primary citation | Lu, H.,Komukai, Y.,Usami, K.,Guo, Y.,Qiao, X.,Nukaga, M.,Hoshino, T. Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity. J.Chem.Inf.Model., 62:6762-6774, 2022 Cited by PubMed: 36184946DOI: 10.1021/acs.jcim.2c00537 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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