7XI3
Crystal Structure of the NPAS4-ARNT2 heterodimer in complex with DNA
Summary for 7XI3
Entry DOI | 10.2210/pdb7xi3/pdb |
Descriptor | Aryl hydrocarbon receptor nuclear translocator 2, Neuronal PAS domain protein 4, DNA (5'-D(P*GP*GP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*TP*GP*AP*T)-3'), ... (4 entities in total) |
Functional Keywords | transcription-dna complex, transcription/dna |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 92323.42 |
Authors | Sun, X.N.,Jing, L.Q.,Li, F.W.,Wu, D.L. (deposition date: 2022-04-11, release date: 2022-11-02, Last modification date: 2023-11-29) |
Primary citation | Sun, X.,Jing, L.,Li, F.,Zhang, M.,Diao, X.,Zhuang, J.,Rastinejad, F.,Wu, D. Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family. Proc.Natl.Acad.Sci.USA, 119:e2208804119-e2208804119, 2022 Cited by PubMed: 36343253DOI: 10.1073/pnas.2208804119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.274 Å) |
Structure validation
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