7XHK

High-resolution X-ray cocrystal structure of USP7 in complex with LX04-46

Summary for 7XHK

• Entry DOI: 10.2210/pdb7xhk/pdb
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, ~{N}-[[4-[6-[[1-[[2-chloranyl-4-(furan-2-yl)phenyl]methyl]-4-oxidanyl-piperidin-4-yl]methyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-3-yl]phenyl]methyl]methanamide (3 entities in total)
• Functional Keywords: inhibitor, usp7, complex, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40855.51

Authors

Sun, H.B.,Wen, X.A. (deposition date: 2022-04-08, release date: 2023-06-14, Last modification date: 2023-11-29)

• Primary citation: Wen, X.A.; High-resolution X-ray cocrystal structure of USP7 in complex with LX04-46; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)