7XF5
Full length human CLC-2 channel in apo state
Summary for 7XF5
Entry DOI | 10.2210/pdb7xf5/pdb |
EMDB information | 33169 |
Descriptor | Chloride channel protein 2 (1 entity in total) |
Functional Keywords | homo-dimer, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 197284.70 |
Authors | Wang, L. (deposition date: 2022-04-01, release date: 2023-05-03, Last modification date: 2023-11-15) |
Primary citation | Ma, T.,Wang, L.,Chai, A.,Liu, C.,Cui, W.,Yuan, S.,Wing Ngor Au, S.,Sun, L.,Zhang, X.,Zhang, Z.,Lu, J.,Gao, Y.,Wang, P.,Li, Z.,Liang, Y.,Vogel, H.,Wang, Y.T.,Wang, D.,Yan, K.,Zhang, H. Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14:3424-, 2023 Cited by DOI: 10.1038/s41467-023-39218-6PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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