7XEE

Crystal Structure of the Y53F/N55A mutant of LEH complexed with 2-(3-phenyloxetan-3-yl)ethanamine

Summary for 7XEE

• Entry DOI: 10.2210/pdb7xee/pdb
• Descriptor: Limonene-1,2-epoxide hydrolase, 2-(3-phenyloxetan-3-yl)ethanamine, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: limonene-1, 2-epoxide hydrolase, mutant, rhodococcus erythropolis, hydrolase
• Biological source: Rhodococcus erythropolis
• Total number of polymer chains: 2
• Total formula weight: 35156.46

Authors

Qu, G.,Li, X.,Sun, Z.T. (deposition date: 2022-03-31, release date: 2023-01-18, Last modification date: 2023-11-29)

• Primary citation: Li, J.K.,Qu, G.,Li, X.,Tian, Y.,Cui, C.,Zhang, F.G.,Zhang, W.,Ma, J.A.,Reetz, M.T.,Sun, Z.; Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.; Nat Commun, 13:7813-7813, 2022; PubMed: 36535947; DOI: 10.1038/s41467-022-35468-y

Experimental method

X-RAY DIFFRACTION (1.877 Å)