7XBU

Crystal structure of the adenylation domain of CmnG in complex with capreomycidine

Summary for 7XBU

Entry DOI	10.2210/pdb7xbu/pdb
Descriptor	CmnG, (2S)-amino[(4R)-2-amino-1,4,5,6-tetrahydropyrimidin-4-yl]ethanoic acid (3 entities in total)
Functional Keywords	adenylation, biosynthetic protein
Biological source	Saccharothrix mutabilis subsp. capreolus
Total number of polymer chains	1
Total formula weight	56414.56
Authors	Chen, I.H.,Wang, Y.L.,Chang, C.Y. (deposition date: 2022-03-22, release date: 2023-03-01, Last modification date: 2023-11-29)
Primary citation	Chen, I.H.,Cheng, T.,Wang, Y.L.,Huang, S.J.,Hsiao, Y.H.,Lai, Y.T.,Toh, S.I.,Chu, J.,Rudolf, J.D.,Chang, C.Y. Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis. Chembiochem, 23:e202200563-e202200563, 2022 Cited by PubMed: 36278314 DOI: 10.1002/cbic.202200563 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation