7XBN

Crystal Structure of YC-17-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238

Summary for 7XBN

• Entry DOI: 10.2210/pdb7xbn/pdb
• Descriptor: Cytochrome P450 monooxygenase PikC, PROTOPORPHYRIN IX CONTAINING FE, 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, ... (6 entities in total)
• Functional Keywords: oxidoreductase, yc-17-bound, pikc, unnatural amino acid
• Biological source: Streptomyces venezuelae
• Total number of polymer chains: 2
• Total formula weight: 101608.83

Authors

Li, G.B.,Pan, Y.J.,Li, S.Y.,Gao, X. (deposition date: 2022-03-21, release date: 2023-02-15, Last modification date: 2023-11-29)

• Primary citation: Pan, Y.J.,Li, G.B.,Gao, X.,Li, S.Y.; New mechanistic insight of cytochrome P450 PikC gained from site-specific mutagenesis by non-coding amino acids; Nat Commun, 2023

Experimental method

X-RAY DIFFRACTION (2 Å)