7XBI

The crystal structure of human TrkA kinase bound to the inhibitor

7XBI の概要

• エントリーDOI: 10.2210/pdb7xbi/pdb
• 分子名称: High affinity nerve growth factor receptor, 4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{N}-[3-(1-methylpyrazol-4-yl)-1~{H}-indazol-5-yl]-2-(trifluoromethyl)benzamide, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: kinase, inhibitor, trka, ntrk, cytosolic protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35989.67

構造登録者

Wu, C.Y.,Wang, G.,Ouyang, L. (登録日: 2022-03-21, 公開日: 2023-03-29, 最終更新日: 2023-11-29)

• 主引用文献: Wu, C.Y.,Wang, G.,Ouyang, L.; The crystal structure of human TrkA kinase bound to the inhibitor; To be published,

実験手法

X-RAY DIFFRACTION (2.16 Å)