7XB5

Structure of the ligand-binding domain of S. cerevisiae Upc2 in fusion with T4 lysozyme

Summary for 7XB5

Entry DOI	10.2210/pdb7xb5/pdb
Descriptor	fusion protein of Sterol uptake control protein 2 and Endolysin (1 entity in total)
Functional Keywords	ergosterol, transcription factor, ligand-binding, zinc finger, transcription
Biological source	Saccharomyces cerevisiae S288C More
Total number of polymer chains	1
Total formula weight	52253.81
Authors	Tan, L.,Im, Y.J. (deposition date: 2022-03-20, release date: 2022-09-07, Last modification date: 2023-11-29)
Primary citation	Tan, L.,Chen, L.,Yang, H.,Jin, B.,Kim, G.,Im, Y.J. Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18:1253-1262, 2022 Cited by PubMed: 36229681 DOI: 10.1038/s41589-022-01117-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.44 Å)

Structure validation