7X6T

Discovery of Selective BRD4 BD1 Inhibitor Based on [1,2,4] triazolo [4,3-b] pyridazine Scaffold

7X6T の概要

• エントリーDOI: 10.2210/pdb7x6t/pdb
• 分子名称: Isoform C of Bromodomain-containing protein 4, (2~{R})-2-[[3-methyl-6-(2-phenoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]amino]propanamide (3 entities in total)
• 機能のキーワード: bromodomain, dna binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15128.47

構造登録者

Cao, D.,Xiong, B. (登録日: 2022-03-08, 公開日: 2023-03-22, 最終更新日: 2023-11-29)

• 主引用文献: Hanyue, Z.,Cao, D.,Li, Y.,Du, Z.,Xiong, B.; Discovery of Selective BRD4 BD1 Inhibitor Based on [1,2,4] triazolo [4,3-b] pyridazine Scaffold; To Be Published,

実験手法

X-RAY DIFFRACTION (1.44 Å)