7X3Z
Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NAD
Summary for 7X3Z
Entry DOI | 10.2210/pdb7x3z/pdb |
Descriptor | 17-beta-hydroxysteroid dehydrogenase type 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, ... (4 entities in total) |
Functional Keywords | 17beta-hsd1, estrone, functional analyses, oxidoreductase, steroid, nad/nadh |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 71575.22 |
Authors | |
Primary citation | Li, T.,Song, X.,Stephen, P.,Yin, H.,Lin, S.X. New insights into the substrate inhibition of human 17 beta-hydroxysteroid dehydrogenase type 1. J.Steroid Biochem.Mol.Biol., 228:106246-106246, 2023 Cited by PubMed: 36634828DOI: 10.1016/j.jsbmb.2023.106246 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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