7X2K
Crystal structure of nanobody Nb70 with antibody 1F11 fab and SARS-CoV-2 RBD
Summary for 7X2K
Entry DOI | 10.2210/pdb7x2k/pdb |
Descriptor | Spike protein S1, 1F11-H, 1F11-L, ... (6 entities in total) |
Functional Keywords | sars-cov-2, nanobody, spike, receptor binding domain, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2) More |
Total number of polymer chains | 4 |
Total formula weight | 82195.44 |
Authors | Wang, X.Q.,Zhang, L.Q.,Ren, Y.F.,Li, M.X. (deposition date: 2022-02-25, release date: 2022-12-21, Last modification date: 2023-06-28) |
Primary citation | Li, M.,Ren, Y.,Aw, Z.Q.,Chen, B.,Yang, Z.,Lei, Y.,Cheng, L.,Liang, Q.,Hong, J.,Yang, Y.,Chen, J.,Wong, Y.H.,Wei, J.,Shan, S.,Zhang, S.,Ge, J.,Wang, R.,Dong, J.Z.,Chen, Y.,Shi, X.,Zhang, Q.,Zhang, Z.,Chu, J.J.H.,Wang, X.,Zhang, L. Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13:7957-7957, 2022 Cited by PubMed: 36575191DOI: 10.1038/s41467-022-35642-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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