7X1U

Structure of Thyrotropin-Releasing Hormone Receptor bound with an Endogenous Peptide Agonist TRH.

7X1U の概要

• エントリーDOI: 10.2210/pdb7x1u/pdb
• EMDBエントリー: 32950
• 関連するBIRD辞書のPRD_ID: PRD_002371
• 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Thyrotropin-releasing hormone receptor, mini-G alpha q prtoein, ... (6 entities in total)
• 機能のキーワード: thyrotropin-releasing hormone receptor, cryo-em, protirelin, agonist, membrane protein
• 由来する生物種: Bos taurus (cattle); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 145509.60

構造登録者

Yang, F.,Zhang, H.H.,Meng, X.Y.,Li, Y.G.,Zhou, Y.X.,Ling, S.L.,Liu, L.,Shi, P.,Tian, C.L. (登録日: 2022-02-24, 公開日: 2022-08-31, 最終更新日: 2022-09-14)

• 主引用文献: Yang, F.,Zhang, H.,Meng, X.,Li, Y.,Zhou, Y.,Ling, S.,Sun, D.,Lv, P.,Liu, L.,Shi, P.,Tian, C.; Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue.; Cell Res., 32:858-861, 2022; PubMed: 35352031; DOI: 10.1038/s41422-022-00646-6

実験手法

ELECTRON MICROSCOPY (3.19 Å)