7WYO
Structure of the EV71 3Cpro with 338 inhibitor
Summary for 7WYO
Entry DOI | 10.2210/pdb7wyo/pdb |
Descriptor | 3C protein, N-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylmethyl)prop-2-enamide (3 entities in total) |
Functional Keywords | ev71 3cpro, inhibitor, viral protein, hydrolase-hydrolase inhibitor complex |
Biological source | Enterovirus A71 |
Total number of polymer chains | 2 |
Total formula weight | 41279.35 |
Authors | |
Primary citation | Qin, B.,Craven, G.B.,Hou, P.,Chesti, J.,Lu, X.,Child, E.S.,Morgan, R.M.L.,Niu, W.,Zhao, L.,Armstrong, A.,Mann, D.J.,Cui, S. Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease. Acta Pharm Sin B, 12:3924-3933, 2022 Cited by PubMed: 35702321DOI: 10.1016/j.apsb.2022.06.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.402 Å) |
Structure validation
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