7WWF
Crystal structure of BioH3 from Mycolicibacterium smegmatis
Summary for 7WWF
Entry DOI | 10.2210/pdb7wwf/pdb |
Descriptor | Esterase, DI(HYDROXYETHYL)ETHER, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | mycolicibacterium smegmatis, bioh3, crystal, biosynthetic protein |
Biological source | Mycolicibacterium smegmatis MC2 155 |
Total number of polymer chains | 6 |
Total formula weight | 182709.52 |
Authors | Yang, J.,Xu, Y.C.,Gan, J.H.,Feng, Y.J. (deposition date: 2022-02-12, release date: 2022-07-06, Last modification date: 2023-01-18) |
Primary citation | Xu, Y.,Yang, J.,Li, W.,Song, S.,Shi, Y.,Wu, L.,Sun, J.,Hou, M.,Wang, J.,Jia, X.,Zhang, H.,Huang, M.,Lu, T.,Gan, J.,Feng, Y. Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18:e1010615-e1010615, 2022 Cited by PubMed: 35816546DOI: 10.1371/journal.ppat.1010615 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
Download full validation report