7WVM
The complex structure of PD-1 and cemiplimab
Summary for 7WVM
Entry DOI | 10.2210/pdb7wvm/pdb |
Descriptor | Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1 (3 entities in total) |
Functional Keywords | pd-1, antibody, n58 glycosylation, cemiplimab, immune checkpoint therapy (ict), antitumor protein, immune system-antitumor protein complex, immune system/antitumor protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 74873.37 |
Authors | |
Primary citation | Lu, D.,Xu, Z.,Zhang, D.,Jiang, M.,Liu, K.,He, J.,Ma, D.,Ma, X.,Tan, S.,Gao, G.F.,Chai, Y. PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy. Front Immunol, 13:826045-826045, 2022 Cited by PubMed: 35309324DOI: 10.3389/fimmu.2022.826045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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