7WVA
Crystal structure of mouse Cryptochrome 1 in complex with TH401 compound
Summary for 7WVA
Entry DOI | 10.2210/pdb7wva/pdb |
Descriptor | Cryptochrome-1, 2-(1-methylbenzimidazol-2-yl)sulfanyl-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]ethanamide (3 entities in total) |
Functional Keywords | circadian, clock, cryptochrome, cry, cry1, circadian clock protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 1 |
Total formula weight | 57786.21 |
Authors | Miller, S.A.,Hirota, T. (deposition date: 2022-02-10, release date: 2022-09-07, Last modification date: 2023-11-29) |
Primary citation | Yagi, M.,Miller, S.,Nagai, Y.,Inuki, S.,Sato, A.,Hirota, T. A methylbenzimidazole derivative regulates mammalian circadian rhythms by targeting Cryptochrome proteins. F1000Res, 11:1016-1016, 2022 Cited by PubMed: 36226040DOI: 10.12688/f1000research.124658.1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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