7WU2
Cryo-EM structure of the adhesion GPCR ADGRD1 in complex with miniGs
Summary for 7WU2
Entry DOI | 10.2210/pdb7wu2/pdb |
EMDB information | 32817 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
Functional Keywords | adhesion gpcr, adgrd1, g protein, complex, signal transduction, membrane protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 130701.91 |
Authors | |
Primary citation | Qu, X.,Qiu, N.,Wang, M.,Zhang, B.,Du, J.,Zhong, Z.,Xu, W.,Chu, X.,Ma, L.,Yi, C.,Han, S.,Shui, W.,Zhao, Q.,Wu, B. Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604:779-785, 2022 Cited by PubMed: 35418679DOI: 10.1038/s41586-022-04580-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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