7WLW

X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with SKF89976a

Summary for 7WLW

Entry DOI	10.2210/pdb7wlw/pdb
Related	7WGD 7WGT
Descriptor	Sodium-dependent dopamine transporter, Antibody fragment light chain, Antibody Fragment heavy chain, ... (10 entities in total)
Functional Keywords	neurotransmitter transporter, membrane protein
Biological source	Drosophila melanogaster (fruit fly) More
Total number of polymer chains	3
Total formula weight	109178.86
Authors	Penmatsa, A.,Joseph, D. (deposition date: 2022-01-13, release date: 2022-06-29, Last modification date: 2023-11-29)
Primary citation	Joseph, D.,Nayak, S.R.,Penmatsa, A. Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41:e110735-e110735, 2022 Cited by PubMed: 35796008 DOI: 10.15252/embj.2022110735 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation