7WLU

The Flattened Structure of mPIEZO1 in Lipid Bilayer

Summary for 7WLU

• Entry DOI: 10.2210/pdb7wlu/pdb
• EMDB information: 32593
• Descriptor: Piezo-type mechanosensitive ion channel component 1, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL (2 entities in total)
• Functional Keywords: force, flexible, complex, membrane protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 3
• Total formula weight: 879263.36

Authors

Yang, X.,Lin, C.,Chen, X.,Li, S.,Li, X.,Xiao, B. (deposition date: 2022-01-13, release date: 2022-04-13, Last modification date: 2024-06-26)

• Primary citation: Yang, X.,Lin, C.,Chen, X.,Li, S.,Li, X.,Xiao, B.; Structure deformation and curvature sensing of PIEZO1 in lipid membranes.; Nature, 604:377-383, 2022; PubMed: 35388220; DOI: 10.1038/s41586-022-04574-8

Experimental method

ELECTRON MICROSCOPY (6.81 Å)