7WGW

NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter

7WGW の概要

• エントリーDOI: 10.2210/pdb7wgw/pdb
• 分子名称: DNA (20-MER), CYCLIC GUANOSINE MONOPHOSPHATE (2 entities in total)
• 機能のキーワード: 8-oxo-7, 8-dihydroguanine, g-quadruplex, bloom syndrome protein, guanine metabolite, dna
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 6659.35

構造登録者

Wang, K.B.,Liu, Y.,Li, Y.,Li, J.,Dickerhoff, J.,Yang, M.H.,Yang, D.,Kong, L.Y. (登録日: 2021-12-29, 公開日: 2022-05-18, 最終更新日: 2024-05-15)

• 主引用文献: Wang, K.B.,Liu, Y.,Li, Y.,Dickerhoff, J.,Li, J.,Yang, M.H.,Yang, D.,Kong, L.Y.; Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.; J.Am.Chem.Soc., 144:6361-6372, 2022; PubMed: 35352895; DOI: 10.1021/jacs.2c00435

実験手法