7WGL

X-ray structure of human PPAR delta ligand binding domain-bezafibrate co-crystals obtained by co-crystallization

7WGL の概要

• エントリーDOI: 10.2210/pdb7wgl/pdb
• 分子名称: Peroxisome proliferator-activated receptor delta, octyl beta-D-glucopyranoside, 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, protein-ligand complex, ppar, transcription
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64363.67

構造登録者

Kamata, S.,Honda, A.,Machida, Y.,Uchii, K.,Shiiyama, Y.,Masuda, R.,Oyama, T.,Ishii, I. (登録日: 2021-12-28, 公開日: 2022-05-25, 最終更新日: 2023-11-29)

• 主引用文献: Honda, A.,Kamata, S.,Akahane, M.,Machida, Y.,Uchii, K.,Shiiyama, Y.,Habu, Y.,Miyawaki, S.,Kaneko, C.,Oyama, T.,Ishii, I.; Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate.; Int J Mol Sci, 23:-, 2022; PubMed: 35563117; DOI: 10.3390/ijms23094726

実験手法

X-RAY DIFFRACTION (2.091 Å)