7WGD
X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in substrate-free form.
Summary for 7WGD
| Entry DOI | 10.2210/pdb7wgd/pdb |
| Descriptor | Sodium-dependent dopamine transporter, Antibody fragment (9D5) Light Chain, Antibody fragment (9D5) heavy chain, ... (8 entities in total) |
| Functional Keywords | neurotransmitter transporter, antibody fragment, gaba transporter, membrane protein |
| Biological source | Drosophila melanogaster (fruit fly) More |
| Total number of polymer chains | 3 |
| Total formula weight | 108025.42 |
| Authors | Joseph, D.,Penmatsa, A. (deposition date: 2021-12-28, release date: 2022-06-29, Last modification date: 2023-11-29) |
| Primary citation | Joseph, D.,Nayak, S.R.,Penmatsa, A. Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41:e110735-e110735, 2022 Cited by PubMed: 35796008DOI: 10.15252/embj.2022110735 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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