7WD2

Crystal structure of S43 bound to SARS-CoV-2 RBD

7WD2 の概要

• エントリーDOI: 10.2210/pdb7wd2/pdb
• 分子名称: Spike protein S1, Anti-RON nanobody, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: sars-cov-2, rbd, s43, complex, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 74378.37

構造登録者

Wang, Q.H.,Gao, G.F.,Qi, J.X.,Su, C.,Liu, H.H.,Wu, L.L. (登録日: 2021-12-20, 公開日: 2022-12-21, 最終更新日: 2023-11-29)

• 主引用文献: Liu, H.,Wu, L.,Liu, B.,Xu, K.,Lei, W.,Deng, J.,Rong, X.,Du, P.,Wang, L.,Wang, D.,Zhang, X.,Su, C.,Bi, Y.,Chen, H.,Liu, W.J.,Qi, J.,Cui, Q.,Qi, S.,Fan, R.,Jiang, J.,Wu, G.,Gao, G.F.,Wang, Q.; Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice.; Cell Rep Med, 4:100918-100918, 2023; PubMed: 36702124; DOI: 10.1016/j.xcrm.2023.100918

実験手法

X-RAY DIFFRACTION (2.69 Å)