7W7B
Heme exporter HrtBA in complex with protoporphyrin IX containing manganese(III), high resolution data
Summary for 7W7B
Entry DOI | 10.2210/pdb7w7b/pdb |
Descriptor | Putative ABC transport system, ATP-binding protein, Putative ABC transport system integral membrane protein, (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, ... (6 entities in total) |
Functional Keywords | heme efflux, heme extraction, heme detoxification, abc transporter, 4-helix tmd, atp-binding protein-membrane protein complex, membrane protein |
Biological source | Corynebacterium diphtheriae NCTC 13129 More |
Total number of polymer chains | 12 |
Total formula weight | 366354.24 |
Authors | Hisano, T.,Nakamura, H.,Rahman, M.M.,Tosha, T.,Shirouzu, M.,Shiro, Y. (deposition date: 2021-12-04, release date: 2022-06-22, Last modification date: 2023-11-29) |
Primary citation | Nakamura, H.,Hisano, T.,Rahman, M.M.,Tosha, T.,Shirouzu, M.,Shiro, Y. Structural basis for heme detoxification by an ATP-binding cassette-type efflux pump in gram-positive pathogenic bacteria. Proc.Natl.Acad.Sci.USA, 119:e2123385119-e2123385119, 2022 Cited by PubMed: 35767641DOI: 10.1073/pnas.2123385119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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