7W7B

Heme exporter HrtBA in complex with protoporphyrin IX containing manganese(III), high resolution data

7W7B の概要

• エントリーDOI: 10.2210/pdb7w7b/pdb
• 分子名称: Putative ABC transport system, ATP-binding protein, Putative ABC transport system integral membrane protein, (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, ... (6 entities in total)
• 機能のキーワード: heme efflux, heme extraction, heme detoxification, abc transporter, 4-helix tmd, atp-binding protein-membrane protein complex, membrane protein
• 由来する生物種: Corynebacterium diphtheriae NCTC 13129; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 366354.24

構造登録者

Hisano, T.,Nakamura, H.,Rahman, M.M.,Tosha, T.,Shirouzu, M.,Shiro, Y. (登録日: 2021-12-04, 公開日: 2022-06-22, 最終更新日: 2023-11-29)

• 主引用文献: Nakamura, H.,Hisano, T.,Rahman, M.M.,Tosha, T.,Shirouzu, M.,Shiro, Y.; Structural basis for heme detoxification by an ATP-binding cassette-type efflux pump in gram-positive pathogenic bacteria.; Proc.Natl.Acad.Sci.USA, 119:e2123385119-e2123385119, 2022; PubMed: 35767641; DOI: 10.1073/pnas.2123385119

実験手法

X-RAY DIFFRACTION (3 Å)