7W3Q

Crystal structure of RORgamma in complex with natural inverse agonist

Summary for 7W3Q

• Entry DOI: 10.2210/pdb7w3q/pdb
• Descriptor: Nuclear receptor ROR-gamma, Peptide from Nuclear receptor coactivator 2, (3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol, ... (4 entities in total)
• Functional Keywords: inverse agonist, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 30695.78

Authors

Tian, S.Y.,Li, Y. (deposition date: 2021-11-25, release date: 2022-12-07, Last modification date: 2023-11-29)

• Primary citation: Tian, S.Y.,Li, Y.; Crystal structure of RORgamma in complex with natural inverse agonist; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)