7W3P
Crystal structure of RORgamma in complex with natural inverse agonist
Summary for 7W3P
Entry DOI | 10.2210/pdb7w3p/pdb |
Descriptor | Nuclear receptor ROR-gamma, Peptide from Nuclear receptor coactivator 2, (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol, ... (4 entities in total) |
Functional Keywords | inverse agonist, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 30679.78 |
Authors | Tian, S.Y.,Li, Y. (deposition date: 2021-11-25, release date: 2022-12-07, Last modification date: 2023-11-29) |
Primary citation | Tian, S.Y.,Li, Y. Crystal structure of RORgamma in complex with natural inverse agonist To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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